Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease
نویسندگان
چکیده
منابع مشابه
Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease
Chronic wasting disease (CWD) is a fatal, transmissible prion disease that affects captive and free-ranging deer, elk, and moose. Although the zoonotic potential of CWD is considered low, identification of multiple CWD strains and the potential for agent evolution upon serial passage hinders a definitive conclusion. Surveillance for CWD in free-ranging populations has documented a continual geo...
متن کاملElk use of wallows and potential chronic wasting disease transmission.
Deposition of prions into the environment by infected animals may contribute to transmission and spread of chronic wasting disease (CWD) among free-ranging cervids, and identification of such environmental sources may provide an avenue for managing CWD. We evaluated the role that wallow use by elk (Cervus elaphus) may play in CWD transmission by monitoring wallows with animal-activated cameras ...
متن کاملChronic Wasting Disease and Potential Transmission to Humans
Chronic wasting disease (CWD) of deer and elk is endemic in a tri-corner area of Colorado, Wyoming, and Nebraska, and new foci of CWD have been detected in other parts of the United States. Although detection in some areas may be related to increased surveillance, introduction of CWD due to translocation or natural migration of animals may account for some new foci of infection. Increasing spre...
متن کاملMinor oral lesions facilitate transmission of chronic wasting disease.
While chronic wasting disease (CWD) prion transmission, entry, and trafficking remain incompletely elucidated, natural exposure of the oral and/or nasal mucous membranes seems certain. Cervids commonly sustain minor lesions on oral mucous membranes that could have an impact on susceptibility to prion infection. To explore this potential cofactor, we studied cohorts of cervid PrP transgenic mice...
متن کاملHorizontal Transmission of Chronic Wasting Disease in Reindeer
We challenged reindeer by the intracranial route with the agent of chronic wasting disease sourced from white-tailed deer, mule deer, or elk and tested for horizontal transmission to naive reindeer. Reindeer were susceptible to chronic wasting disease regardless of source species. Horizontal transmission occurred through direct contact or indirectly through the environment.
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2012
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1803.110685